王东锔 博士

主要科研领域与方向

细胞膜的动态变化与形态维持

综合运用活细胞成像、体外重构及细胞原位冷冻电镜技术，探究细胞中的新结构

代表性论文

1. Dongju Wang#; Xia Jia#; Raviv Dharan; Jiahao Ren; Yi Zheng; Xiaopeng Li; Mingtao Huang; Kui Xu; Qi Zhang; Takami Sho; Siyuan Liu; Fan Yang; Qiangfeng Cliff Zhang; Raya Sorkin; Nan Liu; Hong-Wei Wang; Li Yu; Polymerization of Tetraspanin 7 into Helical Transmembrane Skeletons for Tubular Membrane Stabilization, Vita, 2026 (#co-first authors)

2. Dongju Wang#; Haifang Wang#; Wei Wan; Zihui Zhu; Takami Sho; Yi Zheng; Xing Zhang; Longyu Dou; Qiang Ding; Li Yu; Zhihua Liu; Engineered migrasomes provide a robust and thermally stable

vaccination platform, eLife, 2025, 13: RP97621 (#co-first authors)

3. Ben Zuker#; Raviv Dharan#; Dongju Wang#; Li Yu; Raya Sorkin; Michael M.Kozlov; Migrasomeformation is initiated preferentially in tubular junctions by membrane tension, Biophysical Journal, 2025, 124(4): 604-619 (#co-first authors)

4. Dongju Wang; Li Yu; Migrasome biogenesis: when biochemistry meets biophysics on membranes, Trends in Biochemical Sciences, 2024, 49(9): 829-840

5. Kurt S. Van Horn#; Dongju Wang#; Daniel Medina-Cleghorn; Peter S. Lee; Clifford Bryant; Chad Altobelli; Priyadarshini Jaishankar; Kevin K. Leung; Raymond A. Ng; Andrew J. Ambrose; Yinyan Tang; Michelle R. Arkin; Adam R. Renslo; Engaging a Non-catalytic Cysteine Residue Drives Potent and Selective Inhibition of Caspase-6, Journal of the American Chemical Society, 2023, 145(18): 10015-10021(#co-first authors)