房昕燕 博士

北京生物结构前沿研究中心卓越学者

主要科研领域与方向

通过生物物理学方法跨尺度研究EB病毒侵入机制

代表性论文

[1] SUN C^#, XIE C^#, FANG X Y^#, et al. Chimeric Glycoprotein Nanoparticles Elicit Robust Neutralizing Antibodies Against Epstein-Barr Virus[J]. Adv Mater, 2025: e07012.（co-First Author）

[2] XIE C^#, FANG X Y^#, LIU Y T^#, et al. Human herpesvirus 6B glycoprotein B postfusion structure, vulnerability mapping, and receptor recognition[J]. PLoS Pathog, 2025,21(7): e1013300.

[3] FANG X Y^#, SUN C^#, XIE C^#, et al. Structure and Antigenicity of Kaposi's Sarcoma Associated Herpesvirus Glycoprotein B[J]. Adv Sci , 2025, 12(27):e2502231.（co-First Author）

[4] SUN C^#, FANG X Y^#, BU G L^#, et al. Structural basis of Epstein-Barr virus gp350 receptor recognition and neutralization[J]. Cell Rep, 2025, 44(1): 115168. （co-First Author）

[5] ZHAO G X^#, FANG X Y^#, BU G L^#, et al. Potent human monoclonal antibodies targeting Epstein-Barr virus gp42 reveal vulnerable sites for virus infection[J]. Cell Rep Med, 2024, 5(5): 101573. （co-First Author）

[6] Cong Sun^#, Jia-Wen Yang^#, Chu Xie^#, Xin-Yan Fang^#, et al. The structure of HSV-1 gB bound to a potent neutralizing antibody reveals a conservative antigenic domain across herpesviruses. hLife, 2024, 2(3):141-146. (co-First Author)

[7] SUN C^#, KANG Y F^#, FANG X Y^#, et al. A gB nanoparticle vaccine elicits a protective neutralizing antibody response against EBV[J]. Cell Host Microbe, 2023, 31(11):1882-1897 e1810. (co-First Author)