裴高峰 博士

2021 国家奖学金
2022 清华大学综合奖学金（一等）
2023 清华大学CLS博士后基金杰出奖
2023 北京生物结构前沿研究中心卓越学者

主要科研领域与方向

生物大分子相分离

代表性论文

1. Gaofeng Pei#, Xinxin Wang#, Xuebo Quan#, Danqian Geng#, Zhuo Chen, Weifan Xu, Kai Huang*, Tingting Li*, and Pilong Li*. Opposing Roles of Serine and Charge in IDR Condensate Miscibility. Nature Chemical Biology, 2026, accepted.

2. Jiaojiao Wang#, Dewei Wu#, Gaofeng Pei#, Yupei Wang#, Xiaokang Liu, Shuai Tian, Zhiwei Zhang, Xiaolin Zhang, Pilong Li*, Daoxin Xie*, and Xiaoyi Shan*. The pathogen effector BcSSP2 suppresses the NPC phase separation to facilitate Botrytis cinerea infection. Nature Communications, 2025, 16, 8610.

3. Gaofeng Pei#, Heankel Lyons#, Pilong Li*, and Benjamin R. Sabari*. Transcription regulation by biomolecular condensates. Nature Reviews Molecular Cell Biology, 2024, 1-24.

4. Jinnan He#, Xiangru Huo#, Gaofeng Pei#, Zeran Jia#, Yiming Yan, Jiawei Yu, Haozhi Qu, Yunxin Xie, Junsong Yuan, Yuan Zheng, Yanyan Hu, Minglei Shi, Kaiqiang You, Tingting Li, Tianhua Ma, Michael Q. Zhang, Sheng Ding, Pilong Li*, and Yinqing Li*. Dual-role transcription factors stabilize intermediate expression levels. Cell, 2024, 187, 2746-2766.

5. Gaofeng Pei#, Min Zhou#, Weifan Xu, Jing Wang, and Pilong Li*. Phase Separation-Based Biochemical Assays for Biomolecular Interactions. Methods in Molecular Biology, 2023, 2563: 225-236.

6. Jiaojiao Wang#, Gaofeng Pei#, Yupei Wang#, Dewei Wu#, Xiaokang Liu, Gaoming Li, Jianfang He, Xiaolin Zhang, Xiaoyi Shan*, Pilong Li*, and Daoxin Xie*. Phase separation of nuclear pore complex facilitates selective nuclear transport to regulate plant defense against pathogen and pest invasion. Molecular Plant, 2023, 16, 1016-1030.

7. Yuan Wang#, Chunyu Yu#, Gaofeng Pei#, Wen Jia, Tingting Li*, and Pilong Li*. Dissolution of oncofusion transcription factor condensates for cancer therapy. Nature Chemical Biology, 2023, 19, 1223-1234.

8. Gaofeng Pei#, Weifan Xu#, Jun Lan, Xinquan Wang, and Pilong Li*. CEBIT Screening for Inhibitors of the Interaction between SARS-CoV-2 Spike and ACE2. Fundamental Research, 2022, 2, 562-569.

9. Weifan Xu#, Gaofeng Pei#, Hongrui Liu#, Xiaohui Ju, Jing Wang, Qiang Ding, and Pilong Li*. Compartmentalization-aided interaction screening reveals extensive high-order complexes within the SARS-CoV-2 proteome. Cell Reports, 2021, 36, 109482.

10. Yifei Gao#, Gaofeng Pei#, Dongxue Li#, Ru Li, Yanqiu Shao, Qiangfeng Cliff Zhang, and Pilong Li*. Multivalent m6A motifs promote phase separation of YTHDF proteins. Cell Research, 2019, 29, 767-769.