Cyclic Peptide DataBank (CPDB)

Summary

PDB ID	3MTH Go to RCSB ➚
Title	X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL
Method	X-RAY DIFFRACTION
Resolution	1.90 Å
Release Date	1996-01-29
Authors	Whittingham, J.L.; Dodson, E.J.; Moody, P.C.E.; Dodson, G.G.
Source Organism	Sus scrofa
Keywords	HORMONE
Molecular Weight	11.93 kDa
Entity Count	Protein: 2, Nucleic Acid: 0, NA Hybrid: 0
Space Group	H 3
Cell Parameters	a=80.38 Å, b=80.38 Å, c=37.00 Å, α=90.00°, β=90.00°, γ=120.00°
Disulfide Bond	A6-A11;C6-C11
Other Links	Yes
Peptide Chains	A, B, C, D
Peptide Lengths	21, 30

1	GIVEQCCTSI CSLYQLENYC N

1	FVNQHLCGSH LVEALYLVCG ERGFFYTPKA

X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol.

Whittingham, J.L., Chaudhuri, S., Dodson, E.J., Moody, P.C., Dodson, G.G.

Biochemistry, 1995

The Structure of a Rhombohedral R6 Insulin Hexamer that Binds Phenol

Smith, G.D., Dodson, G.G.

Biopolymers, 1992

Phenol Stabilizes More Helix in a New Symmetrical Zinc Insulin Hexamer

Derewenda, U., Derewenda, Z., Dodson, E.J., Dodson, G.G., Reynolds, C.D., Smith, G.D., Sparks, C., Swenson, D.

Nature, 1989

ID	Name	Formula	Molecular Weight
MPB	4-HYDROXY-BENZOIC ACID METHYL ESTER	C8 H8 O3	152.147
CL	CHLORIDE ION	Cl	35.453
ZN	ZINC ION	Zn	65.409

Assembly ID: 1

Details: author_and_software_defined_assembly

Oligomeric State: Hetero 2-mer

Stoichiometry: A1, B1

Assembly ID: 2

Details: author_and_software_defined_assembly

Oligomeric State: Hetero 2-mer

Stoichiometry: A1, B1

Assembly ID: 3