Cyclic Peptide DataBank (CPDB)
Browse and visualize 3D structures of polypeptides
Browse and visualize 3D structures of polypeptides
| PDB ID | 5UDP Go to RCSB ➚ |
| Title | High resolution x-ray crystal structure of synthetic insulin lispro |
| Method | X-RAY DIFFRACTION |
| Resolution | 1.35 Å |
| R-factors | R-work: 0.160, R-free: 0.194 |
| Release Date | 2017-01-11 |
| Authors | Mandal, K.; Dhayalan, B.; Kent, S.B.H. |
| Source Organism | Homo sapiens |
| Keywords | insulin lispro, chemical protein synthesis, Fmoc chemistry, HORMONE |
| Molecular Weight | 35.70 kDa |
| Entity Count | Protein: 2, Nucleic Acid: 0, NA Hybrid: 0 |
| Space Group | P 1 21 1 |
| Cell Parameters | a=46.64 Å, b=61.47 Å, c=59.15 Å, α=90.00°, β=110.60°, γ=90.00° |
| Disulfide Bond | A6-A11;C6-C11;E6-E11;G6-G11;I6-I11;K6-K11 |
| Other Links | Yes |
| Peptide Chains | A, B, C, D, E, F, G, H, I, J, K, L |
| Peptide Lengths | 21, 30 |
| 1 | GIVEQCCTSI CSLYQLENYC N |
| 1 | FVNQHLCGSH LVEALYLVCG ERGFFYTKPT |
Scope and Limitations of Fmoc Chemistry SPPS-Based Approaches to the Total Synthesis of Insulin Lispro via Ester Insulin.
Chemistry, 2017
| ID | Name | Formula | Molecular Weight |
|---|---|---|---|
| IPH | PHENOL | C6 H6 O | 94.111 |
| ZN | ZINC ION | Zn | 65.409 |
| CL | CHLORIDE ION | Cl | 35.453 |
| NA | SODIUM ION | Na | 22.99 |
Assembly ID: 1
Details: author_and_software_defined_assembly
Oligomeric State: Hetero 6-mer
Stoichiometry: A3, B3
Assembly ID: 2
Details: author_and_software_defined_assembly
Oligomeric State: Hetero 6-mer
Stoichiometry: A3, B3