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Cyclic Peptide DataBank (CPDB)

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6OLI - Cyclic Peptide Structure

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Summary

PDB ID6OLI Go to RCSB ➚
TitleStructure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)
MethodELECTRON MICROSCOPY
Resolution3.50 Å
Release Date2019-06-19
AuthorsLi, W.; Cate, J.H.D.
Source OrganismHomo sapiens
Keywordsselective stalling, drug-like molecule, human ribosome nascent chain complex, RIBOSOME
EC Number4.2.99.18
Molecular Weight3175.98 kDa
Entity CountProtein: 76, Nucleic Acid: 7, NA Hybrid: 0
Disulfide Bondn99-n110
Other LinksYes
Peptide Chainso, w, y
Protein ChainsA, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, S2, SA, SB, SC, SD, SE, SF, SG, SH, SI, SJ, SK, SL, SM, SN, SO, SP, SQ, SR, SS, ST, SU, SV, SW, SX, SY, SZ, Sa, Sb, Sc, Sd, Se, Sf, Sg, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h, i, j, k, l, m, n, p, q, r, t, u, v
Peptide Lengths36, 25, 10
Protein Lengths221, 226, 259, 204, 145, 104, 312, 150, 67, 397, 211, 139, 187, 99, 114, 50, 76, 1714, 153, 127, 146, 134, 143, 82, 141, 102, 64, 55, 220, 237, 185, 118, 137, 129, 214, 131, 73, 82, 57, 252, 363, 157, 121, 294, 247, 225, 234, 191, 169, 205, 203, 195, 153, 181, 175, 157, 129, 61, 117, 189, 134, 134, 147, 121, 103, 106, 129, 109, 122, 189, 97, 84, 69, 50, 105, 91, 122, 3607, 76, 98

Sequence Information

Chain: SA - 40S ribosomal protein SA (Length: 221)

1GALDVLQMKE EDVLKFLAAG THLGGTNLDF QMEQYIYKRK SDGIYIINLK RTWEKLLLAA
61RAIVAIENPA DVSVISSRNT GQRAVLKFAA ATGATPIAGR FTPGTFTNQI QAAFREPRLL
121VVTDPRADHQ PLTEASYVNL PTIALCNTDS PLRYVDIAIP CNNKGAHSVG LMWWMLAREV
181LRMRGTISRE HPWEVMPDLY FYRDPEEIEK EEQAAAEKAV T

Chain: SD - 40S ribosomal protein S3 (Length: 226)

1AVQISKKRKF VADGIFKAEL NEFLTRELAE DGYSGVEVRV TPTRTEIIIL ATRTQNVLGE
61KGRRIRELTA VVQKRFGFPE GSVELYAEKV ATRGLCAIAQ AESLRYKLLG GLAVRRACYG
121VLRFIMESGA KGCEVVVSGK LRGQRAKSMK FVDGLMIHSG DPVNYYVDTA VRHVLLRQGV
181LGIKVKIMLP WDPTGKIGPK KPLPDHVSIV EPKDEILPTT PISEQK

Chain: SE - 40S ribosomal protein S4, X isoform (Length: 259)

1ARGPKKHLKR VAAPKHWMLD KLTGVFAPRP STGPHKLREC LPLIIFLRNR LKYALTGDEV
61KKICMQRFIK IDGKVRTDIT YPAGFMDVIS IDKTGENFRL IYDTKGRFAV HRITPEEAKY
121KLCKVRKIFV GTKGIPHLVT HDARTIRYPD PLIKVNDTIQ IDLETGKITD FIKFDTGNLC
181MVTGGANLGR IGVITNRERH PGSFDVVHVK DANGNSFATR LSNIFVIGKG NKPWISLPRG
241KGIRLTIAEE RDKRLAAKQ

Chain: SI - 40S ribosomal protein S8 (Length: 204)

1GISRDNWHKR RKTGGKRKPY HKKRKYELGR PAANTKIGPR RIHTVRVRGG NKKYRALRLD
61VGNFSWGSEC CTRKTRIIDV VYNASNNELV RTKTLVKNCI VLIDSTPYRQ WYESHYALPL
121GRKKGAKLTP EEEEILNKKR SKKIQKKYDE RKKNAKISSL LEEQFQQGKL LACIASRPGQ
181CGRADGYVLE GKELEFYLRK IKAR

Chain: SS - 40S ribosomal protein S18 (Length: 145)

1MSLVIPEKFQ HILRVLNTNI DGRRKIAFAI TAIKGVGRRY AHVVLRKADI DLTKRAGELT
61EDEVERVITI MQNPRQYKIP DWFLNRQKDV KDGKYSQVLA NGLDNKLRED LERLKKIRAH
121RGLRHFWGLR VRGQHTKTTG RRGRT

Chain: SU - 40S ribosomal protein S20 (Length: 104)

1AIHRIRITLT SRNVKSLEKV CADLIRGAKE KNLKVKGPVR MPTKTLRITT RKTPCGEGSK
61TWDRFQMRIH KRLIDLHSPS EIVKQITSIS IEPGVEVEVT IADA

Chain: Sg - Receptor of activated protein C kinase 1 (Length: 312)

1EQMTLRGTLK GHNGWVTQIA TTPQFPDMIL SASRDKTIIM WKLTRDETNY GIPQRALRGH
61SHFVSDVVIS SDGQFALSGS WDGTLRLWDL TTGTTTRRFV GHTKDVLSVA FSSDNRQIVS
121GSRDKTIKLW NTLGVCKYTV QDESHSEWVS CVRFSPNSSN PIIVSCGWDK LVKVWNLANC
181KLKTNHIGHT GYLNTVTVSP DGSLCASGGK DGQAMLWDLN EGKHLYTLDG GDIINALCFS
241PNRYWLCAAT GPSIKIWDLE GKIIVDELKQ EVISTSSKAE PPQCTSLAWS ADGQTLFAGY
301TDNLVRVWQV TI

Chain: SN - 40S ribosomal protein S13 (Length: 150)

1GRMHAPGKGL SQSALPYRRS VPTWLKLTSD DVKEQIYKLA KKGLTPSQIG VILRDSHGVA
61QVRFVTGNKI LRILKSKGLA PDLPEDLYHL IKKAVAVRKH LERNRKDKDA KFRLILIESR
121IHRLARYYKT KRVLPPNWKY ESSTASALVA

Chain: Sf - 40S ribosomal protein S27a (Length: 67)

1YTTPKKNKHK RKKVKLAVLK YYKVDENGKI SRLRRECPSD ECGAGVFMAS HFDRHYCGKC
61CLTYCFN

Chain: B - 60S ribosomal protein L3 (Length: 397)

1SHRKFSAPRH GSLGFLPRKR SSRHRGKVKS FPKDDPSKPV HLTAFLGYKA GMTHIVREVD
61RPGSKVNKKE VVEAVTIVET PPMVVVGIVG YVETPRGLRT FKTVFAEHIS DECKRRFYKN
121WHKSKKKAFT KYCKKWQDED GKKQLEKDFS SMKKYCQVIR VIAHTQMRLL PLRQKKAHLM
181EIQVNGGTVA EKLDWARERL EQQVPVNQVF GQDEMIDVIG VTKGKGYKGV TSRWHTKKLP
241RKTHRGLRKV ACIGAWHPAR VAFSVARAGQ KGYHHRTEIN KKIYKIGQGY LIKDGKLIKN
301NASTDYDLSD KSINPLGGFV HYGEVTNDFV MLKGCVVGTK KRVLTLRKSL LVQTKRRALE
361KIDLKFIDTT SKFGHGRFQT MEEKKAFMGP LKKDRIA

Chain: K - 60S ribosomal protein L10 (Length: 211)

1RRPARCYRYC KNKPYPKSRF CRGVPDAKIR IFDLGRKKAK VDEFPLCGHM VSDEYEQLSS
61EALEAARICA NKYMVKSCGK DGFHIRVRLH PFHVIRINKM LSCAGADRLQ TGMRGAFGKP
121QGTVARVHIG QVIMSIRTKL QNKEHVIEAL RRAKFKFPGR QKIHISKKWG FTKFNADEFE
181DMVAEKRLIP DGCGVKYIPN RGPLDKWRAL H

Chain: N - 60S ribosomal protein L14 (Length: 139)

1VFRRFVEVGR VAYVSFGPHA GKLVAIVDVI DQNRALVDGP CTQVRRQAMP FKCMQLTDFI
61LKFPHSAHQK YVRQAWQKAD INTKWAATRW AKKIEARERK AKMTDFDRFK VMKAKKMRNR
121IIKNEVKKLQ KAALLKASP

Chain: R - 60S ribosomal protein L18 (Length: 187)

1GVDIRHNKDR KVRRKEPKSQ DIYLRLLVKL YRFLARRTNS TFNQVVLKRL FMSRTNRPPL
61SLSRMIRKMK LPGRENKTAV VVGTITDDVR VQEVPKLKVC ALRVTSRARS RILRAGGKIL
121TFDQLALDSP KGCGTVLLSG PRKGREVYRH FGKAPGTPHS HTKPYVRSKG RKFERARGRR
181ASRGYKN

Chain: V - 60S ribosomal protein L22 (Length: 99)

1VLKFTLDCTH PVEDGIMDAA NFEQFLQERI KVNGKAGNLG GGVVTIERSK SKITVTSEVP
61FSKRYLKYLT KKYLKKNNLR DWLRVVANSK ESYELRYFQ

Chain: h - 60S ribosomal protein L34 (Length: 114)

1VQRLTYRRRL SYNTASNKTR LSRTPGNRIV YLYTKKVGKA PKSACGVCPG RLRGVRAVRP
61KVLMRLSKTK KHVSRAYGGS MCAKCVRDRI KRAFLIEEQK IVVKVLKAQA QSQK

Chain: n - 60S ribosomal protein L40 (Length: 50)

1IEPSLRQLAQ KYNCDKMICR KCYARLHPRA VNCRKKKCGH TNNLRPKKKV

Chain: u - tRNA (Length: 76)

1GCCCGGAUAG CUCAGUCGGU AGAGCAGGGG AUUCCGUAUC CCCGUGUCCU UGGUUCGAUU
61CCGAGUCCGG GCACCA

Chain: y - Nascent chain (Length: 36)

1XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXX

Chain: S2 - 18S ribosomal RNA (Length: 1714)

1UACCUGGUUG AUCCUGCCAG UAGCAUAUGC UUGUCUCAAA GAUUAAGCCA UGCAUGUCUA
61AGUACGCACG GCCGGUACAG UGAAACUGCG AAUGGCUCAU UAAAUCAGUU AUGGUUCCUU
121UGGUCGCUCG CUCCUCUCCC ACUUGGAUAA CUGUGGUAAU UCUAGAGCUA AUACAUGCCG
181ACGGGCGCUG ACCCCCUUCG CGGGGGGGAU GCGUGCAUUU AUCAGUGGUG ACUCUAGAUA
241ACCUCGGGCC GAUCGCACGC CCCCCGUGGC GGCGACGACC CAUUCGAACG UCUGCCCUAU
301CAACUUUCGA UGGUAGUCGC CGUGCCUACC AUGGUGACCA CGGGUGACGG GGAAUCAGGG
361UUCGAUUCCG GAGAGGGAGC CUGAGAAACG GCUACCACAU CCAAGGAAGG CAGCAGGCGC
421GCAAAUUACC CACUCCCGAC CCGGGGAGGU AGUGACGAAA AAUAACAAUA CAGGACUCUU
481UCGAGGCCCU GUAAUUGGAA UGAGUCCACU UUAAAUCCUU CCGCGAGGAU CCAUUGGAGG
541GCAAGUCUGG UGCCAGCAGC CGCGGUAAUU CCAGCUCCAA UAGCGUAUAU UAAAGUUGCU
601GCAGUUAAAA AGCUCGUAGU UGGAUCUUGG GAGCGGGCGU CCCCGCCCUC UCGGCCGGGG
661CCCGAAGCAU UUACUUUGAA AAAAUUAGAG UGUUCAAAGC AGGCCCGAGC CGCCUGGAUA
721CCGCAGCUAG GAAUAAUGGA AUAGGACCGC GGUUCUAUUU UGUUGGUUUU CGGAACUGAG
781GCCAUGAUUA AGAGGGACGG CCGGGGGCAU UCGUAUUGCG CCGCUAGAGG UGAAAUUCUU
841GGACCGGCGC AAGACGGACC AGAGCGAAAG CAUUUGCCAA GAAUGUUUUC AUUAAUCAAG
901AACGAAAGUC GGAGGUUCGA AGACGAUCAG AUACCGUCGU AGUUCCGACC AUAAACGAUG
961CCGACUGGCG AUGCGGCGGC GUUAUUCCCA UGACCCGCCG GGCAGCUUCC GGGAAACCAA
1021AGUCUUUGGG UUCCGGGGGG AGUAUGGUUG CAAAGCUGAA ACUUAAAGGA AUUGACGGAA
1081GGGCACCACC AGGAGUGGAG CCUGCGGCUU AAUUUGACXC AACACGGGAA ACCUCACCCG
1141GCCCGGACAC GGACAGGAUU GACAGAUUGA UAGCUCUUUC UCGAUUCCGU GGGUGGUGGU
1201GCAUGGCNGU UCUUAGUUGG UGGAGCGAUU UGUCUGGUUA AUUCCGAUAA CGAACGAGAC
1261UCUGGCAUGC UAACUAGUUA CGCGACCCCC GAGCGGUCGG CGUCCCCCAA CUUCUUAGAG
1321GGACAAGUGG CGUUCAGCCA CCCGAGAUUG AGCAAUAACA GGUCUGUGAU GCCCUUAGAU
1381GUCCGGGGCU GCACGCGCGC UACACUGACU GGCUCAGCGU GUGCCUACCC UACGCCGGCA
1441GGCGCGGGUA ACCCGUUGAA CCCCAUUCGU GAUGGGGAUC GGGGAUUGCA AUUAUUCCCC
1501AUGAACGAGG AAUUCCCAGU AAGUGCGGGU CAUAAGCUUG CGUUGAUUAA GUCCCUGCCC
1561UUUGUACACA CCGCCCGUCG CUACUACCGA UUGGAUGGUU UAGUGAGGCC CUCGGAUCGG
1621CCCGGAGCGC UGAGAAGACG GUCGAACUUG ACUAUCUAGA GGAAGUAAAA GUCGUAACAA
1681GGUUUCNGUA GGUGAACCUG CGGAAGGAUC AUUA

Chain: SL - 40S ribosomal protein S11 (Length: 153)

1ADIQTERAYQ KQPTIFQNKK RVLLGETGKE KLPRYYKNIG LGFKTPKEAI EGTYIDKKCP
61FTGNVSIRGR ILSGVVTKMK MQRTIVIRRD YLHYIRKYNR FEKRHKNMSV HLSPCFRDVQ
121IGDIVTVGEC RPLSKTVRFN VLKVTKAAGT KKQ

Chain: SP - 40S ribosomal protein S15 (Length: 127)

1RTFRKFTYRG VDLDQLLDMS YEQLMQLYSA RQRRRLNRGL RRKQHSLLKR LRKAKKEAPP
61MEKPEVVKTH LRDMIILPEM VGSMVGVYNG KTFNQVEIKP EMIGHYLGEF SITYKPVKHG
121RPGIGAT

Chain: SQ - 40S ribosomal protein S16 (Length: 146)

1MPSKGPLQSV QVFGRKKTAT AVAHCKRGNG LIKVNGRPLE MIEPRTLQYK LLEPVLLLGK
61ERFAGVDIRV RVKGGGHVAQ IYAIRQSISK ALVAYYQKYV DEASKKEIKD ILIQYDRTLL
121VADPRRCESK KFGGPGARAR YQKSYR

Chain: SR - 40S ribosomal protein S17 (Length: 134)

1GRVRTKTVKK AARVIIEKYY TRLGNDFHTN KRVCEEIAII PSKKLRNKIA GYVTHLMKRI
61QRGPVRGISI KLQEEERERR DNYVPEVSAL DQEIIEVDPD TKEMLKLLDF GSLSNLQVTQ
121PTVGMNFKTP RGPV

Chain: ST - 40S ribosomal protein S19 (Length: 143)

1PGVTVKDVNQ QEFVRALAAF LKKSGKLKVP EWVDTVKLAK HKELAPYDEN WFYTRAASTA
61RHLYLRGGAG VGSMTKIYGG RQRNGVMPSH FSRGSKSVAR RVLQALEGLK MVEKDQDGGR
121KLTPQGQRDL DRIAGQVAAA NKK

Chain: SV - 40S ribosomal protein S21 (Length: 82)

1MQNDAGEFVD LYVPRKCSAS NRIIGAKDHA SIQMNVAEVD KVTGRFNGQF KTYAICGAIR
61RMGESDDSIL RLAKADGIVS KN

Chain: SX - 40S ribosomal protein S23 (Length: 141)

1GKCRGLRTAR KLRSHRRDQK WHDKQYKKAH LGTALKANPF GGASHAKGIV LEKVGVEAKQ
61PNSAIRKCVR VQLIKNGKKI TAFVPNDGCL NFIEENDEVL VAGFGRKGHA VGDIPGVRFK
121VVKVANVSLL ALYKGKKERP R

Chain: Sa - 40S ribosomal protein S26 (Length: 102)

1TKKRRNNGRA KKGRGHVQPI RCTNCARCVP KDKAIKKFVI RNIVEAAAVR DISEASVFDA
61YVLPKLYVKL HYCVSCAIHS KVVRNRSREA RKDRTPPPRF RP

Chain: Sc - 40S ribosomal protein S28 (Length: 64)

1RVQPIKLARV TKVLGRTGSQ GQCTQVRVEF MDDTSRSIIR NVKGPVREGD VLTLLESERE
61ARRL

Chain: Sd - 40S ribosomal protein S29 (Length: 55)

1GHQQLYWSHP RKFGQGSRSC RVCSNRHGLI RKYGLNMCRQ CFRQYAKDIG FIKLD

Chain: SC - 40S ribosomal protein S2 (Length: 220)

1EWMPVTKLGR LVKDMKIKSL EEIYLFSLPI KESEIIDFFL GASLKDEVLK IMPVQKQTRA
61GQRTRFKAFV AIGDYNGHVG LGVKCSKEVA TAIRGAIILA KLSIVPVRRG YWGNKIGKPH
121TVPCKVTGRC GSVLVRLIPA PRGTGIVSAP VPKKLLMMAG IDDCYTSARG CTATLGNFAK
181ATFDAISKTY SYLTPDLWKE TVFTKSPYQE FTDHLVKTHT

Chain: SG - 40S ribosomal protein S6 (Length: 237)

1MKLNISFPAT GCQKLIEVDD ERKLRTFYEK RMATEVAADA LGEEWKGYVV RISGGNDKQG
61FPMKQGVLTH GRVRLLLSKG HSCYRPRRTG ERKRKSVRGC IVDANLSVLN LVIVKKGEKD
121IPGLTDTTVP RRLGPKRASR IRKLFNLSKE DDVRQYVVRK PLNKEGKKPR TKAPKIQRLV
181TPRVLQHKRR RIALKKQRTK KNKEEAAEYA KLLAKRMKEA KEKRQEQIAK RRRLSSL

Chain: SJ - 40S ribosomal protein S9 (Length: 185)

1PVARSWVCRK TYVTPRRPFE KSRLDQELKL IGEYGLRNKR EVWRVKFTLA KIRKAARELL
61TLDEKDPRRL FEGNALLRRL VRIGVLDEGK MKLDYILGLK IEDFLERRLQ TQVFKLGLAK
121SIHHARVLIR QRHIRVRKQV VNIPSFIVRL DSQKHIDFSL RSPYGGGRPG RVKRKNAKKG
181QGGAG

Chain: SM - 40S ribosomal protein S12 (Length: 118)

1NTALQEVLKT ALIHDGLARG IREAAKALDK RQAHLCVQAS NCDEPMYVKL VEALLAEHQI
61NLIKVDDNKK LGEWVGLCKI DREGNPRKVV GCSCVVVKDY GKESQAKDVI EEYFKCKK

Chain: SO - 40S ribosomal protein S14 (Length: 137)

1ISLGPQVAEG ENVFGVCHIF ASFNDTFVHV TDLSGKETIC RVTGGMKVKA DRDESSPYAA
61MLAAQDVAQR CKELGITALH IKLRATGGNR TKTPGPGAQS ALRALARSGM KIGRIEDVTP
121IPSDSTRRKG GRRGRRL

Chain: SW - 40S ribosomal protein S15a (Length: 129)

1VRMNVLADAL KSINNAEKRG KRQVLIRPCS KVIVRFLTVM MKHGYIGEFE IIDDHRAGKI
61VVNLTGRLNK CGVISPRFDV QLKDLEKWQN NLLPSRQFGF IVLTTSAGIM DHEEARRKHT
121GGKILGFFF

Chain: SB - 40S ribosomal protein S3a (Length: 214)

1VVDPFSKKDW YDVKAPAMFN IRNIGKTLVT RTQGTKIASD GLKGRVFEVS LADLQNDEVA
61FRKFKLITED VQGKNCLTNF HGMDLTRDKM CSMVKKWQTM IEAHVDVKTT DGYLLRLFCV
121GFTKKRNNQI RKTSYAQHQQ VRQIRKKMME IMTREVQTND LKEVVNKLIP DSIGKDIEKA
181CQSIYPLHDV FVRKVKMLKK PKFELGKLME LHGE

Chain: SY - 40S ribosomal protein S24 (Length: 131)

1NDTVTIRTRK FMTNRLLQRK QMVIDVLHPG KATVPKTEIR EKLAKMYKTT PDVIFVFGFR
61THFGGGKTTG FGMIYDSLDY AKKNEPKHRL ARHGLYEKKK TSRKQRKERK NRMKKVRGTA
121KANVGAGKKP K

Chain: SZ - 40S ribosomal protein S25 (Length: 73)

1KLNNLVLFDK ATYDKLCKEV PNYKLITPAV VSERLKIRGS LARAALQELL SKGLIKLVSK
61HRAQVIYTRN TKG

Chain: Sb - 40S ribosomal protein S27 (Length: 82)

1PLAKDLLHPS PEEEKRKHKK KRLVQSPNSY FMDVKCPGCY KITTVFSHAQ TVVLCVGCST
61VLCQPTGGKA RLTEGCSFRR KQ

Chain: Se - 40S ribosomal protein S30 (Length: 57)

1VHGSLARAGK VRGQTPKVAK QEKKKKKTGR AKRRMQYNRR FVNVVPTFGK KKGPNAN

Chain: A - 60S ribosomal protein L8 (Length: 252)

1GRVIRGQRKG AGSVFRAHVK HRKGAARLRA VDFAERHGYI KGIVKDIIHD PGRGAPLAKV
61VFRDPYRFKK RTELFIAAEG IHTGQFVYCG KKAQLNIGNV LPVGTMPEGT IVCCLEEKPG
121DRGKLARASG NYATVISHNP ETKKTRVKLP SGSKKVISSA NRAVVGVVAG GGRIDKPILK
181AGRAYHKYKA KRNCWPRVRG VAMNPVEHPF GGGNHQHIGK PSTIRRDAPA GRKVGLIAAR
241RTGRLRGTKT VQ

Chain: C - 60S ribosomal protein L4 (Length: 363)

1CARPLISVYS EKGESSGKNV TLPAVFKAPI RPDIVNFVHT NLRKNNRQPY AVSELAGHQT
61SAESWGTGRA VARIPRVRGG GTHRSGQGAF GNMCRGGRMF APTKTWRRWH RRVNTTQKRY
121AICSALAASA LPALVMSKGH RIEEVPELPL VVEDKVEGYK KTKEAVLLLK KLKAWNDIKK
181VYASQRMRAG KGKMRNRRRI QRRGPCIIYN EDNGIIKAFR NIPGITLLNV SKLNILKLAP
241GGHVGRFCIW TESAFRKLDE LYGTWRKAAS LKSNYNLPMH KMINTDLSRI LKSPEIQRAL
301RAPRKKIHRR VLKKNPLKNL RIMLKLNPYA KTMRRNTILR QARNHKLRVD KAAAAAAALQ
361AKS

Chain: D - 5.8S ribosomal RNA (Length: 157)

1CGACUCUUAG CGGUGGAUCA CUCGGCUCGU GCGUCGAUGA AGAACGCAGC UAGCUGCGAG
61AAUUAAUGUG AAUUGCAGGA CACAUUGAUC AUCGACACUU CGAACGCACU UGCGGCCCCG
121GGUUCCUCCC GGGGCUACGC CUGUCUGAGC GUCGCUU

Chain: E - 5S ribosomal RNA (Length: 121)

1GUCUACGGCC AUACCACCCU GAACGCGCCC GAUCUCGUCU GAUCUCGGAA GCUAAGCAGG
61GUCGGGCCUG GUUAGUACUU GGAUGGGAGA CCGCCUGGGA AUACCGGGUG CUGUAGGCUU
121U

Chain: F - 60S ribosomal protein L5 (Length: 294)

1VKVVKNKAYF KRYQVKFRRR REGKTDYYAR KRLVIQDKNK YNTPKYRMIV RVTNRDIICQ
61IAYARIEGDM IVCAAYAHEL PKYGVKVGLT NYAAAYCTGL LLARRLLNRF GMDKIYEGQV
121EVTGDEYNVE SIDGQPGAFT CYLDAGLART TTGNKVFGAL KGAVDGGLSI PHSTKRFPGY
181DSESKEFNAE VHRKHIMGQN VADYMRYLME EDEDAYKKQF SQYIKNSVTP DMMEEMYKKA
241HAAIRENPVY EKKPKKEVKK KRWNRPKMSL AQKKDRVAQK KASFLRAQER AAES

Chain: G - 60S ribosomal protein L6 (Length: 247)

1PHCSRNPVLV RGIGRYSRSA MYSRKAMYKR KYSAAKSKVE KKKKEKVLAT VTKPVGGDKN
61GGTRVVKLRK MPRYYPTEDV PRKLLSHGKK PFSQHVRKLR ASITPGTILI ILTGRHRGKR
121VVFLKQLASG LLLVTGPLVL NRVPLRRTHQ KFVIATSTKI DISNVKIPKH LTDAYFKKKK
181LRKPRHQEGE IFDTEKEKYE ITEQRKIDQK AVDSQILPKI KAIPQLQGYL RSVFALTNGI
241YPHKLVF

Chain: H - 60S ribosomal protein L7 (Length: 225)

1NFAELKIKRL RKKFAQKMLR KARRKLIYEK AKHYHKEYRQ MYRTEIRMAR MARKAGNFYV
61PAEPKLAFVI RIRGINGVSP KVRKVLQLLR LRQIFNGTFV KLNKASINML RIVEPYIAWG
121YPNLKSVNEL IYKRGYGKIN KKRIALTDNA LIARSLGKYG IICMEDLIHE IYTVGKRFKE
181ANNFLWPFKL SSPRGGMKKK TTHFVEGGDA GNREDQINRL IRRMN

Chain: I - 60S ribosomal protein L7a (Length: 234)

1NPLFEKRPKN FGIGQDIQPK RDLTRFVKWP RYIRLQRQRA ILYKRLKVPP AINQFTQALD
61RQTATQLLKL AHKYRPETKQ EKKQRLLARA EKKAAGKGDV PTKRPPVLRA GVNTVTTLVE
121NKKAQLVVIA HDVDPIELVV FLPALCRKMG VPYCIIKGKA RLGRLVHRKT CTTVAFTQVN
181SEDKGALAKL VEAIRTNYND RYDEIRRHWG GNVLGPKSVA RIAKLEKAKA KELA

Chain: J - 60S ribosomal protein L9 (Length: 191)

1MKTILSNQTV DIPENVDITL KGRTVIVKGP RGTLRRDFNH INVELSLLGK KKKRLRVDKW
61WGNRKELATV RTICSHVQNM IKGVTLGFRY KMRSVYAHFP INVVIQENGS LVEIRNFLGE
121KYIRRVRMRP GVACSVSQAQ KDELILEGND IELVSNSAAL IQQATTVKNK DIRKFLDGIY
181VSEKGTVQQA D

Chain: L - 60S ribosomal protein L11 (Length: 169)

1ENPMRELRIR KLCLNICVGE SGDRLTRAAK VLEQLTGQTP VFSKARYTVR SFGIRRNEKI
61AVHCTVRGAK AEEILEKGLK VREYELRKNN FSDTGNFGFG IQEHIDLGIK YDPSIGIYGL
121DFYVVLGRPG FSIADKKRRT GCIGAKHRIS KEEAMRWFQQ KYDGIILPG

Chain: M - 60S ribosomal protein L13 (Length: 205)

1APSRNGMVLK PHFHKDWQRR VATWFNQPAR KIRRRKARQA KARRIAPRPA SGPIRPIVRC
61PTVRYHTKVR AGRGFSLEEL RVAGIHKKVA RTIGISVDPR RRNKSTESLQ ANVQRLKEYR
121SKLILFPRKP SAPKKGDSSA EELKLATQLT GPVMPVRNVY KKEKARVITE EEKNFKAFAS
181LRMARANARL FGIRAKRAKE AAEQD

Chain: O - 60S ribosomal protein L15 (Length: 203)

1GAYKYIQELW RKKQSDVMRF LLRVRCWQYR QLSALHRAPR PTRPDKARRL GYKAKQGYVI
61YRIRVRRGGR KRPVPKGATY GKPVHHGVNQ LKFARSLQSV AEERAGRHCG ALRVLNSYWV
121GEDSTYKFFE VILIDPFHKA IRRNPDTQWI TKPVHKHREM RGLTSAGRKS RGLGKGHKFH
181HTIGGSRRAA WRRRNTLQLH RYR

Chain: P - 60S ribosomal protein L13a (Length: 195)

1QVLVLDGRGH LLGRLAAIVA KQVLLGRKVV VVRCEGINIS GNFYRNKLKY LAFLRKRMNT
61NPSRGPYHFR APSRIFWRTV RGMLPHKTKR GQAALDRLKV FDGIPPPYDK KKRMVVPAAL
121KVVRLKPTRK FAYLGRLAHE VGWKYQAVTA TLEEKRKEKA KIHYRKKKQL MRLRKQAEKN
181VEKKIDKYTE VLKTH

Chain: Q - 60S ribosomal protein L17 (Length: 153)

1VRYSLDPENP TKSCKSRGSN LRVHFKNTRE TAQAIKGMHI RKATKYLKDV TLQKQCVPFR
61RYNGGVGRCA QAKQWGWTQG RWPKKSAEFL LHMLKNAESN AELKGLDVDS LVIEHIQVNK
121APKMRRRTYR AHGRINPYMS SPCHIEMILT EKE

Chain: S - 60S ribosomal protein L19 (Length: 181)

1SMLRLQKRLA SSVLRCGKKK VWLDPNETNE IANANSRQQI RKLIKDGLII RKPVTVHSRA
61RCRKNTLARR KGRHMGIGKR KGTANARMPE KVTWMRRMRI LRRLLRRYRE SKKIDRHMYH
121SLYLKVKGNV FKNKRILMEH IHKLKADKAR KKLLADQAEA RRSKTKEARK RREERLQAKK
181E

Chain: T - 60S ribosomal protein L18a (Length: 175)

1MKASGTLREY KVVGRCLPTP KCHTPPLYRM RIFAPNHVVA KSRFWYFVSQ LKKMKKSSGE
61IVYCGQVFEK SPLRVKNFGI WLRYDSRSGT HNMYREYRDL TTAGAVTQCY RDMGARHRAR
121AHSIQIMKVE EIAASKCRRP AVKQFHDSKI KFPLPHRVLR RQHKPRFTTK RPNTF

Chain: U - 60S ribosomal protein L21 (Length: 157)

1TNTKGKRRGT RYMFSRPFRK HGVVPLATYM RIYKKGDIVD IKGMGTVQKG MPHKCYHGKT
61GRVYNVTQHA VGIVVNKQVK GKILAKRINV RIEHIKHSKS RDSFLKRVKE NDQKKKEAKE
121KGTWVQLKRQ PAPPREAHFV RTNGKEPELL EPIPYEF

Chain: W - 60S ribosomal protein L23 (Length: 129)

1AKFRISLGLP VGAVINCADN TGAKNLYIIS VKGIKGRLNR LPAAGVGDMV MATVKKGKPE
61LRKKVHPAVV IRQRKSYRRK DGVFLYFEDN AGVIVNNKGE MKGSAITGPV AKECADLWPR
121IASNAGSIA

Chain: X - 60S ribosomal protein L24 (Length: 61)

1KVELCSFSGY KIYPGHGRRY ARTDGKVFQF LNAKCESAFL SKRNPRQINW TVLYRRKHKK
61G

Chain: Y - 60S ribosomal protein L23a (Length: 117)

1KIRTSPTFRR PKTLRLRRQP KYPRKSAPRR NKLDHYAIIK FPLTTESAMK KIEDNNTLVF
61IVDVKANKHQ IKQAVKKLYD IDVAKVNTLI RPDGEKKAYV RLAPDYDALD VANKIGI

Chain: SF - 40S ribosomal protein S5 (Length: 189)

1DIKLFGKWST DDVQINDISL QDYIAVKEKY AKYLPHSAGR YAAKRFRKAQ CPIVERLTNS
61MMMHGRNNGK KLMTVRIVKH AFEIIHLLTG ENPLQVLVNA IINSGPREDS TRIGRAGTVR
121RQAVDVSPLR RVNQAIWLLC TGAREAAFRN IKTIAECLAD ELINAAKGSS NSYAIKKKDE
181LERVAKSNR

Chain: Z - 60S ribosomal protein L26 (Length: 134)

1MKFNPFVTSD RSKNRKRHFN APSHIRRKIM SSPLSKELRQ KYNVRSMPIR KDDEVQVVRG
61HYKGQQIGKV VQVYRKKYVI YIERVQREKA NGTTVHVGIH PSKVVITRLK LDKDRKKILE
121RKAKSRQVGK EKGK

Chain: a - 60S ribosomal protein L27 (Length: 134)

1KFMKPGKVVL VLAGRYSGRK AVIVKNIDDG TSDRPYSHAL VAGIDRYPRK VTAAMGKKKI
61AKRSKIKSFV KVYNYNHLMP TRYSVDIPLD KTVVNKDVFR DPALKRKARR EAKVKFEERY
121KTGKNKWFFQ KLRF

Chain: b - 60S ribosomal protein L27a (Length: 147)

1PSRLRKTRKL RGHVSHGHGR IGKHRKHPGG RGNAGGLHHH RINFDKYHPG YFGKVGMKHY
61HLKRNQSFCP TVNLDKLWTL VSEQTRVNAA KNKTGAAPII DVVRSGYYKV LGKGKLPKQP
121VIVKAKFFSR RAEEKIKSVG GACVLVA

Chain: c - 60S ribosomal protein L29 (Length: 121)

1AKSKNHTTHN QSRKWHRNGI KKPRSQRYES LKGVDPKFLR NMRFAKKHNK KGLKKMQANN
61AKAMSARAEA IKALVKPKEV KPKIPKGVSR KLDRLAYIAH PKLGKRARAR IAKGLRLCRP
121K

Chain: d - 60S ribosomal protein L30 (Length: 103)

1TKKSLESINS RLQLVMKSGK YVLGYKQTLK MIRQGKAKLV ILANNCPALR KSEIEYYAML
61AKTGVHHYSG NNIELGTACG KYYRVCTLAI IDPGDSDIIR SMP

Chain: e - 60S ribosomal protein L31 (Length: 106)

1NEVVTREYTI NIHKRIHGVG FKKRAPRALK EIRKFAMKEM GTPDVRIDTR LNKAVWAKGI
61RNVPYRIRVR LSRKRNEDED SPNKLYTLVT YVPVTTFKNL QTVNVD

Chain: f - 60S ribosomal protein L32 (Length: 129)

1AALRPLVKPK IVKKRTKKFI RHQSDRYVKI KRNWRKPRGI DNRVRRRFKG QILMPNIGYG
61SNKKTKHMLP SGFRKFLVHN VKELEVLLMC NKSYCAEIAH NVSSKNRKAI VERAAQLAIR
121VTNPNARLR

Chain: g - 60S ribosomal protein L35a (Length: 109)

1SGRLWSKAIF AGYKRGLRNQ REHTALLKIE GVYARDETEF YLGKRCAYVY KAKNNTVTPG
61GKPNKTRVIW GKVTRAHGNS GMVRAKFRSN LPAKAIGHRI RVMLYPSRI

Chain: i - 60S ribosomal protein L35 (Length: 122)

1AKIKARDLRG KKKEELLKQL DDLKVELSQL RVAKVTGGAA SKLSKIRVVR KSIARVLTVI
61NQTQKENLRK FYKGKKYKPL DLRPKKTRAM RRRLNKHEEN LKTKKQQRKE RLYPLRKYAV
121KA

Chain: SH - 40S ribosomal protein S7 (Length: 189)

1SAKIVKPNGE KPDEFESGIS QALLELEMNS DLKAQLRELN ITAAKEIEVG GGRKAIIIFV
61PVPQLKSFQK IQVRLVRELE KKFSGKHVVF IAQRRILPKP TRKSRTKNKQ KRPRSRTLTA
121VHDAILEDLV FPSEIVGKRI RVKLDGSRLI KVHLDKAQQN NVEHKVETFS GVYKKLTGKD
181VNFEFPEFQ

Chain: j - 60S ribosomal protein L36 (Length: 97)

1YPMAVGLNKG HKVTKNVSKP RHSRRRGRLT KHTKFVRDMI REVCGFAPYE RRAMELLKVS
61KDKRALKFIK KRVGTHIRAK RKREELSNVL AAMRKAA

Chain: k - 60S ribosomal protein L37 (Length: 84)

1TKGTSSFGKR RNKTHTLCRR CGSKAYHLQK STCGKCGYPA KRKRKYNWSA KAKRRNTTGT
61GRMRHLKIVY RRFRHGFREG TTPK

Chain: l - 60S ribosomal protein L38 (Length: 69)

1PRKIEEIKDF LLTARRKDAK SVKIKKNKDN VKFKVRCSRY LYTLVITDKE KAEKLKQSLP
61PGLAVKELK

Chain: m - 60S ribosomal protein L39 (Length: 50)

1SSHKTFRIKR FLAKKQKQNR PIPQWIRMKT GNKIRYNSKR RHWRRTKLGL

Chain: o - 60S ribosomal protein L41 (Length: 25)

1MRAKWRKKRM RRLKRKRRKM RQRSK

Chain: p - 60S ribosomal protein L36a (Length: 105)

1VNVPKTRRTF CKKCGKHQPH KVTQYKKGKD SLYAQGKRRY DRKQSGYGGQ TKPIFRKKAK
61TTKKIVLRLE CVEPNCRSKR MLAIKRCKHF ELGGDKKRKG QVIQF

Chain: q - 60S ribosomal protein L37a (Length: 91)

1AKRTKKVGIV GKYGTRYGAS LRKMVKKIEI SQHAKYTCSF CGKTKMKRRA VGIWHCGSCM
61KTVAGGAWTY NTTSAVTVKS AIRRLKELKD Q

Chain: r - 60S ribosomal protein L28 (Length: 122)

1SAHLQWMVVR NCSSFLIKRN KQTYSTEPNN LKARNSFRYN GLIHRKTVGV EPAADGKGVV
61VVIKRRSGQR KPATSYVRTT INKNARATLS SIRHMIRKNK YRPDLRMAAI RRASAILRSQ
121KP

Chain: t - 28S ribosomal RNA (Length: 3607)

1CGCGACCUCA GAUCAGACGU GGCGACCCGC UGAAUUUAAG CAUAUUAGUC AGCGGAGGAA
61AAGAAACUAA CCAGGAUUCC CUCAGUAACG GCGAGUGAAC AGGGAAGAGC CCAGCGCCGA
121AUCCCCGCCC CGCGGGGCGC GGGACAUGUG GCGUACGGAA GACCCGCUCC CCGGCGCCGC
181UCGUGGGGGG CCCAAGUCCU UCUGAUCGAG GCCCAGCCCG UGGACGGUGU GAGGCCGGUA
241GCGGCCCCCG GCGCGCGCCC GGGUCUUCCC GGAGUCGGGU UGCUUGGGAA UGCAGCCCAA
301AGCGGGUGGU AAACUCCAUC UAAGGCUAAA UACCGGCACG AGACCGAUAG UCAACAAGUA
361CCGUAAGGGA AAGUUGAAAA GAACUUUGAA GAGAGAGUUC AAGAGGGCGU GAAACCGUUA
421AGAGGUAAAC GGGUGGGGUC CGCGCAGUCC GCCCGGAGGA UUCAACCCGG CGGCGGGUCC
481GGCCGUGUCG GCGGCCCGGC GGAUCUUUCC CGCCCCCGGG GUCGGCGGGG GACCGUCCCC
541CGGACCGGCG ACCGGCCGCC GCCGGGCGCA UUUCCAGGCG GUGCGCCGCG ACCGGCUCCG
601GGACGGCUGG GAAGGCCCGG CGGGGAAGGU GGCUCGGGGC CCCCGAGUGU UACAGCCCCC
661CCGGCAGCAG CACUCGCCGA AUCCCGGGGC CGAGGGAGCG AGACCCGUCG CCGCGCUCUC
721CCCCCUGGGG GGGCCGGGCC ACCCCUCCCA CGGCGCGACC GCUCUCCCAG GGGGCGGGGC
781GGACUGUCCC CAGUGCGCCC CGGGCGGGUC GCGCCGUCGG GCCCGGGGGG CCACGCGCGC
841GUCCCCCGAA GGGGGGGACG GCGGAGAGCG CACGGGGUCG GCGGCGACGU CGGCUACCCA
901CCCGACCCGU CUUGAAACAC GGACCAAGGA GUCUAACACG UGCGCGAGUC GGGGGCUCGC
961ACGAAAGCCG CCGUGGCGCA AUGAAGGUGA AGGCCGGCGC GCUCGCCGGC CGAGGUGGGA
1021UCCCGAGGCC UCUCCAGUCC GCCGAGGGGC ACCACCGGCC CGUCUCGCCC GCCGCGCCGG
1081GGAGGUGGAG CACGAGCGCA CGUGUUAGGA CCCGAAAGAU GGUGAACUAU GCCUGGGCAG
1141GGCGAAGCCA GAGGAAACUC UGGUGGAGGU CCGUAGCGGU CCUGACGUGC AAAUCGGUCG
1201UCCGACCUGG GUAUAGGGGC GAAAGACUAA UCGAACCAUC UAGUAGCUGG UUCCCUCCGA
1261AGUUUCCCUC AGGAUAGCUG GCGCUCUCGC CCACGCAGUU UUAUCCGGUA AAGCGAAUGA
1321UUAGAGGUCU UGGGGCCGAA ACGAUCUCAA CCUAUUCUCA AACUUUAAAU GGGUAAGAAG
1381CCCGGCUCGC UGGCGUGGAG CCGGGGUGGA AUGCGAGUGC CUAGUGGGCC ACUUUUGGUA
1441AGCAGAACUG GCGCUGCGGG AUGAACCGAA CGCCGGGUUA AGGCGCCCGA UGCCGACGCU
1501CAUCAGACCC CAGAAAAGGU GUUGGUUGAU AUAGACAGCA GGACGGUGGC CAUGGAAGUC
1561GGAAUCCGCU AAGGAGUGUG UAACAACUCA CCUGCCGAAU CAACUAGCCC UGAAAAUGGA
1621UGGCGCUGGA GCGUCGGGCC CAUACCCGGC CGUCGCCGGC GUCGAGAGUG GACGGGAGCG
1681GCGGCCCGGA GCCCCGCGGA CGCUACGCCG CGACGAGUAG GAGGGCCGCU GCGGUGAGCC
1741UUGAAGCCUA GGGCGCGGGC CCGGGUGGAG CCGCCGCAGG UGCAGAUCUU GGUGGUAGUA
1801GCAAAUAUUC AAACGAGAAC UUUGAAGGCC GAAGUGGAGA AGGGUUCCAU GUGAACAGCA
1861GUUGAACAUG GGUCAGUCGG UCCUGAGAGA UGGGCGAGCG CCGUUCCGAA GGGACGGGCG
1921AUGGCCUCCG UUGCCCUCGG CCGAUCGAAA GGGAGUCGGG UUCAGAUCCC CGAAUCCGGA
1981GUGGCGGAGA UGGGCGCCGC GAGGCGUCCA GUGCGGUAAC GCGACCGAUC CCGGAGAAGC
2041CGGCGGGAGC CCCGGGGAGA GUUCUCUUUU CUUUGUGAAG GGCAGGGCGC CCUGGAAUGG
2101GUUCGCCCCG AGAGAGGGGC CCGUGCCUUG GAAAGCGUCG CGGUUCCGGC GGCGUCCGGU
2161GAGCUCUCGC UGGCCCUUGA AAAUCCGGGG GAGAGGGUGU AAAUCUCGCG CCGGGCCGUA
2221CCCAUAUCCG CAGCAGGUCU CCAAGGUGAA CAGCCUCUGG CAUGUUGGAA CAAUGUAGGU
2281AAGGGAAGUC GGCAAGCCGG AUCCGUAACU UCGGGAUAAG GAUUGGCUCU AAGGGCUGGC
2341AGCCGACUUA GAACUGGUGC GGACCAGGGG AAUCCGACUG UUUAAUUAAA ACAAAGCAUC
2401GCGAAGGCCC GCGGCGGGUG UUGACGCGAU GUGAUUUCUG CCCAGUGCUC UGAAUGUCAA
2461AGUGAAGAAA UUCAAUGAAG CGCGGGUAAA CGGCGGGAGU AACUAUGACU CUCUUAAGGU
2521AGCCAAAUGC CUCGUCAUCU AAUUAGUGAC GCGCAUGAAU GGAUGAACGA GAUUCCCACU
2581GUCCCUACCU ACUAUCCAGC GAAACCACAG CCAAGGGAAC GGGCUUGGCG GAAUCAGCGG
2641GGAAAGAAGA CCCUGUUGAG CUUGACUCUA GUCUGGCACG GUGAAGAGAC GUUUUUUCAC
2701UGACCCGGUG AGGCGGGGGG GCGAGCCCGA GGGGCUCUCG CUUCUGGCGC CAAGCGCCCG
2761CCCGGCCGGG CGCGACCCGC UCCGGGGACA GUGCCAGGUG GGGAGUUUGA CUGGGGCGGU
2821ACACCUGUCA AACGGUAACG CAGGUGUCCU AAGGCGAGCU CAGGGAGGAC AGAAACCUCC
2881CGUGGAGCAG AAGGGCAAAA GCUCGCUUGA UCUUGAUUUU CAGUACGAAU ACAGACCGUG
2941AAAGCGGGGC CUCACGAUCC UUCUGACCUU UUGGGUUUUA AGCAGGAGGU GUCAGAAAAG
3001UUACCACAGG GAUAACUGGC UUGUGGCGGC CAAGCGUUCA UAGCGACGUC GCUUUUUGAU
3061CCUUCGAUGU CGGCUCUUCC UAUCAUUGUG AAGCAGAAUU CGCCAAGCGU UGGAUUGUUC
3121ACCCACUAAU AGGGAACGUG AGCUGGGUUU AGACCGUCGU GAGACAGGUU AGUUUUACCC
3181UACUGAUGAU GUGUUGUUGC CAUGGUAAUC CUGCUCAGUA CGAGAGGAAC CGCAGGUUCA
3241GACAUUUGGU GUAUGUGCUU GGCUGAGGAG CCAAUGGGGC GAAGCUACCA UCUGUGGGAU
3301UAUGACUGAA CGCCUCUAAG UCAGAAUCCC GCCCAGGCGG AACGAUACGG CAGCGCCGCG
3361GAGCCUCGGU UGGCCUCGGA UAGCCGGUCC CCGCCGGGGG UCCGGUGCGG AGUGCCCUUC
3421GUCCUGGGAA ACGGGGCGCG GCCGGAAAGG CGGCCGCCCC CUCGCCCGUC ACGCACCGCA
3481CGUUCGUGGG GAACCUGGCG CUAAACCAUU CGUAGACGAC CUGCUUCUGG GUCGGGGUUU
3541CGUACGUAGC AGAGCAGCUC CCUCGCUGCG AUCUAUUGAA AGUCAGCCCU CGACACAAGG
3601GUUUGUC

Chain: v - tRNA (Length: 76)

1UGCCCGGUAG CCCCGAAGGU AGAGCAGGGG AUUCCGAAUC CCCGUGUCCU UGGUUCGAUU
61CCGAGUCCGG GCACCA

Chain: w - mRNA (Length: 10)

1UUACGGCGGU

Chain: SK - 40S ribosomal protein S10 (Length: 98)

1MLMPKKNRIA IYELLFKEGV MVAKKDVHMP KHPELADKNV PNLHVMKAMQ SLKSRGYVKE
61QFAWRHFYWY LTNEGIQYLR DYLHLPPEIV PATLRRSR

References

Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.

Li, W., Ward, F.R., McClure, K.F., Chang, S.T., Montabana, E., Liras, S., Dullea, R.G., Cate, J.H.D.

Nat Struct Mol Biol, 2019

PubMed: 31160784 | DOI: 10.1038/s41594-019-0236-8

Ligand Information

ID Name Formula Molecular Weight
MGMAGNESIUM IONMg24.305
ZNZINC IONZn65.409
MVMN-(3-chloropyridin-2-yl)-N-[(3R)-piperidin-3-yl]-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)benzamideC22 H20 Cl N7 O433.894

Biological Assemblies

Assembly ID: 1

Details: author_defined_assembly

Oligomeric State: Hetero 76-mer

Stoichiometry: AA1, AB1, AC1, AD1, AE1, AF1, AG1, AH1, AI1, AJ1, AK1, AL1, AM1, AN1, AO1, AP1, AQ1, AR1, AS1, AT1, AU1, AV1, AW1, AX1, AY1, AZ1, Aa1, Ab1, Ac1, Ad1, Ae1, Af1, Ag1, Ah1, Ai1, Aj1, Ak1, Al1, Am1, An1, Ao1, Ap1, Aq1, Ar1, As1, At1, Au1, Av1, Aw1, Ax1, Ay1, Az1, BA1, BB1, BC1, BD1, BE1, BF1, BG1, BH1, BI1, BJ1, BK1, BL1, BM1, BN1, BO1, BP1, BQ1, BR1, BS1, BT1, BU1, BV1, BW1, BX1

3D Structure Visualization