Cyclic Peptide DataBank (CPDB)

Summary

PDB ID	7JQR Go to RCSB ➚
Title	Abeta 16-36 beta-hairpin mimic with E22G Arctic mutation
Method	X-RAY DIFFRACTION
Resolution	2.07 Å
R-factors	R-work: 0.203, R-free: 0.254
Release Date	2021-09-08
Authors	Kreutzer, A.G.; McKnelly, K.J.; Nowick, J.S.
Source Organism	Homo sapiens
Keywords	Alzheimer's disease, amyloid, Abeta, oligomer, familial mutant, DE NOVO PROTEIN
Molecular Weight	2.10 kDa
Entity Count	Protein: 1, Nucleic Acid: 0, NA Hybrid: 0
Space Group	P 41 3 2
Cell Parameters	a=47.22 Å, b=47.22 Å, c=47.22 Å, α=90.00°, β=90.00°, γ=90.00°
Other Links	Yes
Peptide Chains	A
Peptide Lengths	16

1	VAKLVFFAGA AIIGLM

Effects of Familial Alzheimer's Disease Mutations on the Assembly of a beta-Hairpin Peptide Derived from A beta 16-36 .

McKnelly, K.J., Kreutzer, A.G., Howitz, W.J., Haduong, K., Yoo, S., Hart, C., Nowick, J.S.

Biochemistry, 2022

ID	Name	Formula	Molecular Weight
IOD	IODIDE ION	I	126.904

Assembly ID: 1

Details: author_and_software_defined_assembly

Oligomeric State: Homo 6-mer

Stoichiometry: A6