Cyclic Peptide DataBank (CPDB)
Browse and visualize 3D structures of polypeptides
Browse and visualize 3D structures of polypeptides
| PDB ID | 7TXF Go to RCSB ➚ |
| Title | The allosteric binding mode of alphaD-conotoxin VxXXB |
| Method | X-RAY DIFFRACTION |
| Resolution | 2.47 Å |
| R-factors | R-work: 0.198, R-free: 0.246 |
| Release Date | 2023-04-12 |
| Authors | Ho, T.N.T.; Abraham, N.; Lewis, R.J. |
| Source Organism | Conus vexillum, Lymnaea stagnalis |
| Expression Host | Escherichia coli |
| Keywords | Alpha-conotoxin, Complex, ACETYLCHOLINE-BINDING PROTEIN, CHOLINE-BINDING PROTEIN-ANTAGONIST complex, PEPTIDE BINDING PROTEIN |
| Molecular Weight | 126.24 kDa |
| Entity Count | Protein: 2, Nucleic Acid: 0, NA Hybrid: 0 |
| Space Group | P 21 21 21 |
| Cell Parameters | a=68.91 Å, b=119.57 Å, c=150.73 Å, α=90.00°, β=90.00°, γ=90.00° |
| Disulfide Bond | F4-F16;F9-F26;F14-F28;G4-G16;G9-G26;G14-G28;H4-H16;H9-H26;H14-H28 |
| Peptide Chains | F, G, H |
| Protein Chains | A, B, C, D, E |
| Peptide Lengths | 30 |
| Protein Lengths | 205 |
| 1 | LDRADILYNI RQTSRPDVIP TQRDRPVAVS VSLKFINILE VNEITNEVDV VFWQQTTWSD |
| 61 | RTLAWNSSHS PDQVSVPISS LWVPDLAAYN AISKPEVLTP QLARVVSDGE VLYMPSIRQR |
| 121 | FSCDVSGVDT ESGATCRIKI GSWTHHSREI SVDPTTENSD DSEYFSQYSR FEILDVTQKK |
| 181 | NSVTYSCCPE AYEDVEVSLN FRKKG |
| 1 | TRMCGSMSCP RNGCTCVYHW RRGHGCSCPG |
Unravelling the allosteric binding mode of alpha D-VxXXB at nicotinic acetylcholine receptors.
Front Pharmacol, 2023
Assembly ID: 1
Details: author_defined_assembly
Oligomeric State: Hetero 8-mer
Stoichiometry: A5, B3