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Cyclic Peptide DataBank (CPDB)

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7X41 - Cyclic Peptide Structure

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Summary

PDB ID7X41 Go to RCSB ➚
TitleCrystal structure of chlorotoxin, a glioma specific scorpion toxin
MethodX-RAY DIFFRACTION
Resolution1.15 Å
R-factorsR-work: 0.144, R-free: 0.157
Release Date2023-03-08
AuthorsChang, Y.T.; Chuang, W.J.
Source OrganismLeiurus quinquestriatus quinquestriatus
Expression HostPichia
KeywordsNeurotoxin, Anti-glioma migration agent, Glioma diagnosis, TOXIN
Molecular Weight4.41 kDa
Entity CountProtein: 1, Nucleic Acid: 0, NA Hybrid: 0
Space GroupP 21 21 21
Cell Parametersa=22.34 Å, b=26.01 Å, c=47.23 Å, α=90.00°, β=90.00°, γ=90.00°
Disulfide BondA2-A19;A5-A28;A16-A33;A20-A35
Peptide ChainsA
Peptide Lengths40

Sequence Information

Chain: A - Chlorotoxin (Length: 40)

1EAEAMCMPCF TTDHQMARKC DDCCGGKGRG KCYGPQCLCR

References

Expression in Pichia pastoris and characterization of chlorotoxin, an anti-glioma migration agent

Chang, Y.T.

To be published

Biological Assemblies

Assembly ID: 1

Details: author_defined_assembly

Oligomeric State: Monomer

Stoichiometry: A1

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