Sia You Yang

2025 Advanced Innovation Fellow, The Beijing Frontier Research Center for Biological Structure
2025 Outstanding graduate, Tsinghua University

Main Research Fields

Mechanisms of ATP-dependent chromatin remodelers

Selected Publications

1.  Sia, Y.#, Pan, H.#, Chen, K., & Chen, Z.* (2025). Structural insights into chromatin remodeling by ISWI during active ATP hydrolysis. Science, eadu5654.

2.  Hu, P.#, Sun, J.#, Sun, H.#, Chen, K.#, Sia, Y., Xia, X., Xi, Q.*, & Chen, Z.* (2025). Subnucleosome preference of human chromatin remodeller SMARCAD1. Nature. 1-9.

3.  Tian, Y.#*, Jia, Q.#, Li, M.#, Sia, Y., Hu, P., Chen, K., ... & Chen, Z.* (2025). Regulation of DNA translocation of chromatin remodeler enzyme Chd1 by exit DNA unwrapping. Life Metabolism, 4(3), loaf013.

4.  Li, L.#, Chen, K.#, Sia, Y.#, Hu, P., Ye, Y., & Chen, Z.* (2024). Structure of the ISW1a complex bound to the dinucleosome. Nature Structural & Molecular Biology, 31(2), 266-274.

5.  Chen, K.#, Yuan, J.#, Sia, Y., & Chen, Z.* (2023). Mechanism of action of the SWI/SNF family complexes. Nucleus, 14(1), 2165604.