Contact information

Email:ruiliang@tsinghua.edu.cn

Rui Liang

2025 Excellenct Scholar, Beijing Frontier Research Center for Biological Structure, Tsinghua University
2023 Postdoctoral Foundation at Center for Life Sciences, Tsinghua University
2021 China Scholarship Council Scholarships
2019 First-class scholarship for postgraduate, Huazhong Agricultural University
2016 First-class scholarship for undergraduate, Southwest University

Resume

2013.09-2017.06 College of Veterinary Medicine, Southwest University, Bachelor

2017.09-2023.06 College of Veterinary Medicine, Huazhong Agricultural University, Ph.D.

2022.07-2023.02 School of Medicine, Yale University, Postgraduate Fellow

2023.10-present School of Life Sciences, Tsinghua University, Postdoctoral Researcher

Main Research Fields

(1) the development and application of reverse genetics systems for viruses;

(2) the structural characterization and molecular mechanisms of key viral proteases;

(3) the structural analysis and entry mechanisms of significant zoonotic viral particles.

Selected Publications

1. Liang R, Fu Y, Li G, Shen Z, et al. EP152R-Mediated Endoplasmic Reticulum Stress Contributes to African Swine Fever Virus Infection via the PERK-eIF2α Pathway.  FASEB J. 2024;38(22):e70187.

2. Liang R, Wang G, Zhang D, Ye G, Li M, Shi Y, et al. Structural comparisons of host and African swine fever virus dUTPases reveal new clues for inhibitor development. J Biol Chem. 2021; 296: 100015.

3. Wang G, Hu G, Liang R, Shi J, Qiu X, Yang Y, et al. Establishment of Full-Length cDNA Clones and an Efficient Oral Infection Model for Feline Coronavirus in Cats. J Virol. 2021;95(21): e0074521.

4. Wang G, Liang R, Liu Z, Shen Z, Shi J, Shi Y, et al. The N-Terminal Domain of Spike Protein Is Not the Enteric Tropism Determinant for Transmissible Gastroenteritis Virus in Piglets. Viruses. 2019;11(4):313.