Chaoqun Wu-Beijing Frontier Research Center for Biological Structure

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Home > Faculty > Advanced Innovation Fellow > Chaoqun Wu Return

Contact information

Email：wuchq@mail.tsinghua.edu.cn

Chaoqun Wu

2024 National Scholarship
2025 Distinguished Scholar of the Beijing Frontier Research Center for Biological Structure

Resume

2014.9–2018.6 School of Pharmacy, South-Central University for Nationalities Bachelor

2018.9–2021.6 School of Pharmacy, South-Central University for Nationalities Master

2021.9–2025.6 School of Chemistry, Sun Yat-sen University PhD

2025.9–Present School of Life Sciences, Tsinghua University Postdoctoral Research Fellow

Main Research Fields

Focus on structure-guided research of nucleic acid–related scientific questions and the development of molecular manipulation tools.

Selected Publications

1. Wu CQ, Song HJ, Dai C, Zhang QL, Xing X, Xu L. Building Ligand-Responsive Artificial Signaling Pathways Through Programmable Trans-Acting RNA Circuits in Mammalian Cells. Angew Chem Int Ed Engl. 2025 Nov 24:e11577.

2. Wu CQ^#, Wu RY^#, Zhang QL, Wang LL, Wang Y, Dai C, Zhang CX, Xu L. Harnessing Catalytic RNA Circuits for Construction of Artificial Signaling Pathways in Mammalian Cells. Angew Chem Int Ed Engl. 2024 Apr 2;63(14):e202319309.

3．Wu CQ^#, Feng HY^#, Liu Y, Xu L. Genetically Expressed RNA Strand Displacement for Cellular Manipulation. Chembiochem. 2024 Dec 16;25(24):e202400669.

4. Wu RY^#, Wu CQ^#, Xie F^#, Xing X, Xu L. Building RNA-Mediated Artificial Signaling Pathways between Endogenous Genes. Acc Chem Res. 2024 Jul 2;57(13):1777-1789.

5. Wang LL^#, Wu CQ^#, Zhang QL^#, Wang Y, Liu Y, Yang WJ, Ye SL, Tian Y, Xu L. Chemically Cross-Linked Hammerhead Ribozyme as an Efficient RNA Interference Tool. J Am Chem Soc. 2024 Mar 13;146(10):6665-6674.