Xinyu Xu

2019 National Scholarship for Doctoral Students
2019 Excellent Award of Outstanding Doctoral Scholarship of Beijing Advanced Innovation Center for Structural Biology, Tsinghua University

Main Research Fields

GPCRs play important roles in physiological and pathogenesis, and they are the targets for many clinical drugs. My research aims to elucidate the molecular mechanism for GPCRs signaling through the use of protein engineering strategy, protein crystallography and pharmacology studies.

Selected Publications

1. Xinyu Xu^#, Jonas Kaindl^#, Mary J. Clark^#, Harald Hübner, Kunio Hirata, Roger K.Sunahara*, Peter Gmeiner*, Brian K. Kobilka*, Xiangyu Liu*.(2020). Binding pathway determines norepinephrine selectivity for the human β1AR over β2AR. Cell research. Accepted.

2. Xiangyu Liu^#, Xinyu Xu^#, Daniel Hilger^#, Philipp Aschauer, Johanna K S Tiemann, Yang Du, Hongtao Liu, Kunio Hirata, Xiaoou Sun, Ramon Guixà-González, Jesper M Mathiesen, Peter W Hildebrand, Brian K Kobilka*. (2019). Structural Insights into the Process of GPCR-G Protein Complex Formation. Cell. 177, 1–9.