Yaxian Zhao Ph.D.

Main Research Fields

During my PhD training, I used electrophysiology methods to understand the gating mechanism of membrane-expressing voltage-gated potassium channels. I am currently focusing on characterizing structural properties of cell membrane and membrane proteins, exploiting the state-of-the-art cryoEM technology.

Selected Publications

1. Zhao Y; Goldschen-Ohm MP; Morais-Cabral JH; Chanda B; Robertson GA;. The intrinsically liganded cyclic nucleotide-binding homology domain promotes KCNH channel activation. Journal of General Physiology. 2017, Jan; 149(2): 249-260.

2. Castro-Rodrigues AF, Zhao Y, Fonseca F, Gabant G, Cadene M, Robertson GA, Morais-Cabral JH;. The interaction between the EAG potassium channel and the protein kinase CaMKII involves an extensive interface at the active site of the kinase. Journal of Molecular Biology. 2018. Oct; doi:10.1016/j.jmb.2018.10.015.