Xiangle Ren_Beijing Frontier Research Center for Biological Structure

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Founded in 2015, the Advanced Innovation Center for Structural Biology of Tsinghua University is now headed by the distinguished structural biologist, Prof. Yigong Shi.
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With a focus on structural biology, the Center is developing multidisciplinary strengths in integrating the best practices in method development, fundamental research and translation of research advances, in a bid to deliver some of the original findings with significant influence in the history of science and bolster the biotechnological and biopharmaceutical activities in Beijing.
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Home > Research Team > Advanced Innovation Fellow > Xiangle Ren Return

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Xiangle Ren Ph.D.

2011 National Scholarship
2012 National Scholarship Principal Scholarship/Top Ten University Student Nomination Award
2013 National Scholarship Principal Scholarship/Top Ten University Student Nomination Award
2020 First Prize for Poster Presentation of the 5th National Conference on Developmental Biology
2021 Advanced Innovation Fellow, Beijing Advanced Innovation Center for Structural Biology

Resume

2010-2014Marine College, Shandong University BS.

2014-2020School of medicine, Tsinghua University Ph.D.

2020-PresentSchool of medicine, Tsinghua University Postdoc.

Main Research Fields

Cellular metabolic state and epigenetic landscape are mutually regulated. I will combine structural and functional methods to investigate the recognition of epigenetic modifications and the regulation mechanism of gene expression.

Selected Publications

1. Ren, X., Zhou, Y., Xue, Z., Hao, N., Li, Y., Guo, X., Wang, D., Shi, X. and Li, H. (2021) Histone benzoylation serves as an epigenetic mark for DPF and YEATS family proteins. Nucleic Acids Res, 49, 114-126.

2. Liu, G.*, Zheng, X.*, Guan, H.*, Cao, Y., Qu, H., Kang, J., Ren, X., Lei, J., Dong, M.Q., Li, X. et al. (2019) Architecture of Saccharomyces cerevisiae SAGA complex. Cell Discov, 5, 25.

3. Zhang, W.*, Zhang, X.*, Xue, Z.*, Li, Y.*, Ma, Q., Ren, X., Zhang, J., Yang, S., Yang, L., Wu, M. et al. (2019) Probing the Function of Metazoan Histones with a Systematic Library of H3 and H4 Mutants. Dev Cell, 48, 406-419 e405.