联系方式

电话:+86-10-62797699

传真:+86-10-62784259

邮箱:jllei@tsinghua.edu.cn

雷建林 博士

研究员 中心学术指导委员会成员 冷冻电镜平台主管

个人履历

1989-1993武汉大学物理系 学士

1993-1998武汉大学物理系 博士

1998-2000中国科学院物理研究所 博士后

1999-2000德国慕尼黑大学晶体所 访问学者

2000-2008美国纽约州卫生署沃兹沃什中心 博士后

2008-2009美国哥伦比亚大学生物化学与分子生物物理系 副研究科学家

2008- 至今清华大学生命科学学院 研究员

主要科研领域与方向

主要从事冷冻电镜新技术新方法的开发与应用,尤其侧重于开发高通量冷冻电镜自动化数据采集技术,以及用于提升电子显微镜性能的方法和技术。

代表性论文

1. Agirrezabala, X., Lei, J., Brunelle, J., Ortiz-Meoz, R., Green, R., and Frank, J. (2008). Visualization of the Hybrid State of tRNA Binding Promoted by Spontaneous Ratcheting of the Ribosome. Molecular Cell 32, 190–197.

2. Li, W., Agirrezabala, X., Lei, J., Bouakaz, L., Brunelle, L., Ortiz-Meoz, R., Green, R., Sanyal, S., Ehrenberg, M. and Frank, J. (2008). Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM. The EMBO Journal 27, 3322-3331.

3. Lei, J., and Frank, J. (2005). Automated acquisition of cryo-electron micrographs for Single particle reconstruction on an FEI Tecnai electron microscope. Journal of Structural Biology 150, 69–80.

4. Weidner, E., Frey, F., Lei, J., Pedersen, B., Paulmann, C., and Morgenroth, W. (2004). Disordered quasicrystals: diffuse scattering in decagonal Al-Ni-Fe. J. Appl. Cryst. 37, 802-807

5. Weidner, E., Lei, J., Frey, F., Wang, R., and Grushko, B. (2002). Diffuse scattering in decagonal Al–Ni–Fe. Journal of Alloys and Compounds 342, 156-158.

6. Lei, J., Wang, R., Yin, J., and Duan, X. (2002). Diffuse electron scattering determination of elastic constants of Al–Pd–Mn icosahedral quasicrystal. Journal of Alloys and Compounds 342, 326-329.

7. Wang, R., Hu, C., Lei, J. (2001). Theory of diffuse scattering of quasicrystals due to fluctuations of thermalised phonons and phasons. Phys. Stat. Sol. (b) 225, 21-34.

8. Lei, J., Wang, R., Hu, C., and Ding, D. (2000). Diffuse scattering from dodecagonal quasicrystals. Eur. Phys. J. B 13, 21-30.

9. Wang, R., Hu, C., Lei, J., and Ding, D. (2000). Theoretical aspects of thermal diffuse scattering from quasicrystals. Phys. Rev. B 61, 5843-5845.

10. Lei, J., Wang, R., Hu, C., and Ding, D., (1999). Diffuse scattering from decagonal quasicrystals. Phys. Rev. B 59, 822-828.

11. Lei, J., Hu, C., Wang, R., and Ding, D., (1999). Diffuse scattering from octagonal quasicrystals. J. Phys.: Condens. Matter 11, 1211-1223.

12. Lei, J., Wang, R., Hu, C., and Ding, D. (1998). Diffuse scattering from pentagonal quasicrystals. Phys. Lett. A 247, 343-352.

13. Wang, J., Lei, J., and Wang, R. (1998). Diffraction pattern calculation and phase identification of hypothetical crystalline C3N4. Phys. Rev. B 58, 11890-11895.