电话：+86-10-62782664
邮箱：lixueming@mail.tsinghua.edu.cn
副教授
学术指导委员会成员
1998-2002北京科技大学材料物理系 学士
2002-2005北京科技大学材料物理与化学系 硕士
2005-2009中国科学院物理研究所 博士
2009-2013加州大学旧金山分校 博士后
2014-2017清华大学生命科学学院 助理教授
2017-2019清华大学生命科学学院 副教授
2019-至今清华大学生命科学学院 副教授（长聘）
主要从事冷冻电子显微学理论和方法研究，着重于开发和利用最新的电子显微学技术，以提高冷冻电子显微学三维重构的分辨率到原子水平；同时致力于将电子显微学应用到结构生物学研究中去，以解决与结构相关的重要生物学问题。
1. Ranhao Zhang*, Yuan Shen, Xueming Li# (2024). Tilt-series-based joint CTF estimation for cryo-electron tomography. Structure, 32: 1239-47.
2. Chao Lin*, Li Zhang*, Ziying Zhang*, Yifeng Jiang, Xueming Li#(2023). Locating cellular contents during cryoFIB milling using cellular secondary-electron imaging. Journal of Structural Biology, 215: 108005.
3. Sihan Wang*, Heng Zhou*, Wei Chen*, Yifeng Jiang, Xuzhen Yan, Hong You#, Xueming Li# (2023). CryoFIB milling large tissue samples for cryo-electron tomography. Scientific Reports,13: 5879.
4. Xinyu Zhang*, Tianfang Zhao*, Jiansheng Chen, Yuan Shen#, Xueming Li# (2022). Epicker is an exemplar-based continual learning approach for knowledge accumulation in cryoEM particle picking. Nature Communications, 13(1): 2468
5. Xuzhong Yang*, Chao Lin*, Xudong Chen*, Shouqin Li*, Xueming Li#, Bailong Xiao# (2022). Structure deformation and curvature sensing of PIEZO1 in lipid membranes. Nature, 604(7905):377-383.
6. Mingxu Hu*, Qi Zhang*, Jing Yang#, Xueming Li# (2020). Unit quaternion description of spatial rotations in 3D electron cryo-microscopy, Journal of Structural Biology, 212: 107601
7. Zhaofeng Yan*, Meng Yin*, Jianan Chen*, Xueming Li# (2020). Assembly and Substrate Recognition of Curli Biogenesis System. Nature Communications, 11(1), 241.
8. Li Wang*, Heng Zhou*, Mingmin Zhang*, Wenhao Liu*, Tuan Deng, Qiancheng Zhao, Yiran Li, Jianlin Lei, Xueming Li#, Bailong Xiao#(2019). Structure and mechanogating of the mammalian tactile channel PIEZO2. Nature, 573:225-229.
9. Heng Zhou*, Feng Luo*, Zhipu Luo*, Dan Li, Cong Liu#, Xueming Li# (2019). Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules. Analytical Chemistry, 91(17):10996-11003.
10. Mingxu Hu*, Hongkun Yu*, Kai Gu*, Zhao Wang, Huabin Ruan, Kunpeng Wang, Siyuan Ren, Bing Li, Lin Gan, Shizhen Xu, Guangwen Yang#, Yuan Shen#, Xueming Li# (2018). A particle-filter framework for robust cryoEM 3D reconstruction. Nature Methods, 15, 1083-1089
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