王佳伟 博士

副教授

主要科研领域与方向

膜蛋白晶体学：利用X射线晶体学解析与重大疾病相关的膜蛋白的晶体结构，同时探索利用细聚焦光束线测定微小膜蛋白晶体结构的技术，及微小晶体衍射相位的获取和结构分析等关键科学问题。

代表性论文

1.     Xiaofei Ge, Jiawei Wang^# (2024). Structural mechanism of bacteriophage lambda tail’s interaction with the bacterial receptor. Nature Communications, 15(1):4185.

2.     Zhiwei Gu, Kexun Wu, Jiawei Wang^# (2024). Structural morphing in the viral portal vertex of bacteriophage lambda. Journal of Virology, 98(5):e0006824.

3.     Chang Wang, Jinsong Duan, Zhiwei Gu, Xiaofei Ge, Jianwei Zeng^#, Jiawei Wang^# (2024). Architecture of the bacteriophage lambda tail. Structure, 32(1):35-46.e3.

4.     Ruilian Li, Jinsong Duan, Yicheng Zhou, Jiawei Wang^# (2023). Structural basis of the mechanisms of action and immunity of Lactococcin A, a class IId bacteriocin. Appl Environ Microbiol. 89(3):e0006623.

5.     Chang Wang, Jianwei Zeng^#, Jiawei Wang^# (2022) Structure basis of bacteriophage lambda capsid maturation. Structure. 30(4):637-645.e3.

6.     Liyan Zhu, Jianwei Zeng, Jiawei Wang^# (2022). Structural basis of the immunity mechanisms of pediocin-like bacteriocins. Appl Environ Microbiol. 88(13):e0048122.

7.     Liyan Zhu, Jianwei Zeng, Chang Wang, Jiawei Wang^# (2022) Structural basis of pore formation in the mannose phosphotransferase system by pediocin PA-1. Appl Environ Microbiol. 88(3):e0199221.

8.     Kai Huang, Jianwei Zeng, Xueli Liu, Tianyu Jiang^#, Jiawei Wang^# (2021) Structure of the mannose phosphotransferase system (man-PTS) complexed with microcin E492, a pore-forming bacteriocin. Cell Discovery, 7(1):20.

9.     Linghui Li, Shuliu Dai, George F Gao^#, Jiawei Wang^# (2020) Lattice-translocation defects in specific crystals of the catalytic head domain of influenza neuraminidase. Acta Crystallogr D Struct Biol. 76:1057-1064.

10. Xueli Liu, Jianwei Zeng, Kai Huang, Jiawei Wang^# (2019) Structure of the mannose transporter of the bacterial phosphotransferase system. Cell Research, 29(8):680-682.